Collage of color photos, e.g the Campanile with flags, Cal Band spelling out "USA" on the football field, more.
Photos by Keegan Houser

America250xBerkeley — Innovation, Opportunity, and Civic Courage

Since our founding in 1868, Berkeley has served as a primary engine for the country’s success, transforming the lives of our students and the trajectory of our society. Berkeley research has helped shape modern science and technology; our students and alumni have served in uniform across generations; and the Berkeley campus is a vital laboratory for democracy and civic participation.

In this historic year, few institutions can proudly claim such a varied legacy — to make the nation stronger, to question its choices, and to insist it live up to its ideas — but Berkeley can. On this page, you will find stories and events that illustrate how, through innovation, opportunity, and civic courage, UC Berkeley is and has always been a cornerstone of the American journey.

America 250

America250 Backs College Entrepreneurs with Re-Opening of “America’s Startup” National Competition

Following the success of its inaugural competition earlier this year, America250, the official nonpartisan organization leading the nation’s 250th anniversary celebration, announced the return of America’s Startup, an expanded national collegiate competition designed to identify, support, and celebrate the country’s most promising undergraduate entrepreneurs and early-stage innovators.


Applications are open through October 8, 2026, inviting undergraduate students (or the equivalent) enrolled at accredited U.S. colleges, universities, and trade schools to compete for a share of a $1 million total prize pool — including up to $50,000 in non-dilutive grant funding per team, national mentorship, and a live pitch finale in Washington, D.C.

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INNOVATION

Photo of Victoria Gray

Rewriting the code: The inside story of the first CRISPR cure

Victoria Gray spent 34 years battling the debilitating pain of sickle cell disease. Then she volunteered to be the world’s first “prototype” for a CRISPR therapy — trading a life that felt hopeless for a future she never thought she’d see.

Campanile on a sunny day against a blue sky

25 UC Berkeley breakthroughs to commemorate America’s 250th birthday

As the U.S. observes its 250th birthday, we’re looking back at some of the most notable ideas, people and innovations that have emerged from Berkeley over the course of its history, shaping the fabric of our nation and the world beyond.

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Basic research on Listeria bacteria leads to unique cancer therapy

Microbiologist Daniel Portnoy cofounded a startup that’s turning Listeria into a tool to improve survival in children with leukemia and potentially other cancer patients.

OPPORTUNITY

Former Hope Scholar and current academic achievement counselor Rebeca Borges hugs program director Charly King Beavers at the 20th anniversary celebration.

For 20 years, this UC Berkeley program has helped students who’ve been in foster care succeed

Hope Scholars started with one employee and one student. It has since grown to offer hundreds of students holistic support, including mentorship, emergency funds and move-in day supplies.

Mary Blackburn with three other black students enrolled in the initial year of Berkeley’s Combined Dietetic Internship–Master of Public Health program.

Meet three Black trailblazers in STEM

Berkeley alumni Lloyd Ferguson, Mary Blackburn and Marvin Poston paved the way for Black scientists and engineers. Black Lives at Cal is developing a tour that spotlights their stories.

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To understand youth experiencing homelessness, this UC Berkeley professor hires them

Coco Auerswald has dedicated her life to working with unhoused young people. Doing research alongside them is key to learning about — and solving — youth homelessness, she says.

CIVIC ENGAGEMENT

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For a Berkeley ROTC cadet, the road less traveled rises toward service and leadership

Isshin Shiraishi had no plans for a military education when he arrived at UC Berkeley. Now he’s preparing to serve as cadet commander of the Army ROTC battalion — and he’s made a commitment to service that few students can match.

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Berkeley Talks: Musician Lara Downes celebrates the sound of America

The acclaimed pianist reflects on music’s power to unite across division and express the nation’s most complicated emotions over the past 250 years.

Demonstrators gather outside the capitol building in Boise, Idaho, at the "No Kings" protest

New research says framing protests as fights for civil rights ‘backfires.’ So what might work?

Kim Voss, a UC Berkeley professor of sociology, says appeals rooted in American values may be more effective today than those evoking memories of the Civil Rights Movement.

To learn about other contributions made to our nation across the entire University of California system, visit UC’s America 250 page.